ראשי » About Multiple Sclerosis » Therapeutic information by pharmaceutical companies » Vitamin D enhances interferon-beta-1b response in multiple sclerosis

Vitamin D enhances interferon-beta-1b response in multiple sclerosis

ECTRIMS Online Library. Reder A. Oct 2015

ECTRIMS Online Library. Reder A. | Updated 01.10.2015

Objective: Determine molecular effect of Vitamin D3 on interferon-beta response in mononuclear cells.

Background: Oral vitamin D has additive effects on IFN-b therapy in reducing MRI lesions and clinical activity in MS. The mechanism is unknown, and may be confounded by IFN elevation of serum vitamin D levels, lifestyle, and the subnormal endogenous IFN signaling present in therapy-naïve MS patients.

Conclusions: Vitamin D enhances IFN-beta activation of STAT1 by 100% in untreated patients and by 60% in IFN-treated patients. This increase in interferon signaling may provide a mechanism for benefits of vitamin D in preventing and ameliorating MS, before and during IFN-b therapy. Vitamin D is an inexpensive and safe way to amplify IFN-b’s therapeutic benefit.

22 January 2024

All the practices teach us to start with the silence, the peace and the light that we have within ourselves. Obviously, external situations change and

29 October 2023

EBV infection and its relation to MS is an interesting area of ongoing work. What is EBV? The Epstein-Barr virus (EBV) is one of the

15 July 2023

Telling people that you have MS can be difficult. Accepting the diagnosis yourself is hard, let alone sharing the news with others. Being able to

13 July 2023

Smokers are more likely to progress from relapsing-remitting to progressive MS than non-smokers and have higher levels of long-term disability. Smokers with clinically isolated syndrome

13 July 2023

Menopause is the natural end to a woman’s periods (menstruation). It usually occurs between the ages of 45 and 55 years. Why discuss MS and

13 July 2023

MS is complex and can cause many different symptoms. Early MS may present itself as a history of vague symptoms, which may occur sporadically over a

05 March 2023

No need to pay out of pocket! PassportCard is a cashless system that pays for your medical expenses! Full exemption from deductibles on medical expenses

05 March 2023

An insurance plan that gives you personal protection in case of an accident

Previous Next
Close
Test Caption
Test Description goes like this